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CBD For Gut Health And Weight Loss

Updated: 3 days ago

What is CBD and how does it work in the gut microbiome

CBD, or cannabidiol, is a chemical compound found in cannabis plants. Unlike THC or tetrahydrocannabinol, CBD does not produce psychoactive effects. Instead, it interacts with the endocannabinoid system, which regulates various functions in the body, including mood, appetite, and pain. CBD is thought to have anti-inflammatory and analgesic effects, and it is also being studied for its potential to treat other conditions, such as anxiety and obesity. Some research suggests that CBD may also have a role in gut health. For example, one study found that CBD was able to reduce inflammation in mice with colitis. Additionally, CBD appears to promote the growth of healthy gut bacteria.

Another compound found in cannabis plants and one that Blackhouse Botanicals includes in our products is CBG or cannabigerol. This compound is known for its antimicrobial properties and has been shown to be effective against certain types of bacteria. There is some evidence that CBG may also have beneficial effects on the gut microbiome, including reducing inflammation and supporting the growth of healthy bacteria. However, more research is needed to better understand how CBD and CBG interact with the gut microbiome.

Some researchers have also looked into the potential of terpenes, another compound found in cannabis plants, to affect gut health. Terpenes are compounds that give cannabis plants their distinctive smell and flavor. They are believed to have therapeutic properties, such as anti-inflammatory and antimicrobial effects. Research suggests that terpenes may reduce inflammation in the gut and help maintain a healthy balance between beneficial and harmful bacteria in the microbiome.

Overall, it is clear that compounds found in cannabis plants may have a beneficial effect on gut health. It is important to note that CBD, CBG, and terpenes do not produce any psychoactive effects and won't get you "high" as THC can. Additionally, it is always best to consult with your doctor before trying anything new for your health.

The benefits of CBD for gut health

CBD may be best known for its ability to calm the mind and ease anxiety, but this potent compound can also do wonders for your gut health. CBD is a natural anti-inflammatory and has been shown to help reduce inflammation in the gut, relieving conditions like Crohn's disease and ulcerative colitis. CBD is also beneficial for gut health because it helps to reduce stress and anxiety, two common triggers for gastrointestinal issues. The findings of a recent study on the effects of THC and CBD found several health markers were significantly improved in mouse models including reducing the inflammatory response, improving glucose tolerance, and partially mitigating microbiome dysbiosis (Source). This study also showed, as with many we cite, that CBD was more effective than THC at improving these health markers. The efficacy of CBD vs. THC is a common debate and many believe incorrectly that THC is more psychoactive therefore it must be a more medicinal cannabinoid. CBD is shown to be a more effective treatment for a host of disease pathologies and symptoms in several reputable studies.

Symptoms of and conditions related to microbiome dysbiosis can include:

  • Irritable Bowel Syndrome (IBS)

  • Inflammatory Bowel Disease (IBD)

  • Obesity

  • Cancer

  • Cardiovascular Disease

  • Ulcerative Colitis

  • Crohn's Disease

  • Depression

  • Chronic fatigue

  • Digestive Disorders

  • Indigestion or Acid Reflux

You can see that there are a host of problems created by issues with your gut health. In recent years studies have found strong connections between mental health and physical health related to gut health. This link may help us understand and improve many mental health conditions that modern doctors, psychology and pharmacology have struggled to understand and treat.

The benefits of CBD for weight loss

CBD is effective in gut health and weight loss for a variety of reasons. For one, it helps to reduce inflammation throughout the body, which can lead to weight gain. It also helps to regulate appetite, making it easier to control portion sizes and cravings. One of the more interesting things about CBD is its ability to either increase appetite or decrease appetite in an attempt to return your body to homeostasis. This suggests that whether you are overweight or underweight, CBD regulates your appetite appropriately (Source).

In addition, CBD is known to boost metabolism and promote the breakdown of fat cells. CBD was also shown to promote the browning of fat cells. Brown fat is responsible for burning white fat, the bad fat, in the production of body heat. As a result, it can help the body to more effectively burn calories and shed unwanted pounds (Source). As a bonus, CBD is also thought to aid digestion by stimulating the production of bile in the liver.

In yet another study CBD was shown to:

"promote glucose uptake higher or to equivalent levels, reduce fat accumulation, and reverse the insulin-resistant state of 3T3-L1 cells more effectively, relative to rosiglitazone and metformin" (Source).

It is important to note that CBD and other cannabinoids will not offset calorie intake but have been shown to positively influence early insulin and triglyceride response (Source). What this means is you can't just overeat and expect CBD to do the work for you but it could improve your body's response to food and regulate your appetite. CBD is not like thermogenic fat-burning pills (which have been shown to be unhealthy in repeated studies). It may, however, put your body in a better state to use calories and help build your body's ability to burn fat more efficiently.

When taken regularly, and as studies suggest, CBD can help to improve gut health and promote weight loss. One way to take CBD in lower doses at regular intervals is by using one of our CBD tinctures.

The best CBD products for gut health and weight loss

The gut-brain connection is real, and the impact of what we eat on our gut health is well-documented. So it makes sense that CBD-infused products might be effective for gut health and weight loss. CBD has been shown to help regulate the immune system, reduce inflammation, and improve gut motility. All of these effects could potentially help to promote a healthy gut and support weight loss. In addition, CBD is known to be an appetite suppressant, which could help to reduce cravings and promote a healthy relationship with food if you are overweight. There are a variety of CBD products on the market, so it's important to do your research to find the best one for you. But if you're looking for a natural way to support gut health and weight loss, our high-quality CBD products might be worth a try. Try our 1000 mg CBD Tincture if you are trying to improve gut health, reduce inflammation, improve insulin resistance, and regulate your mood and appetite throughout the day.

FAQs about CBD for gut health and weight loss

1. Can CBD help with gut health?

There is evidence to suggest that CBD may be beneficial for gut health. One study found that CBD was able to reduce inflammation in rats with colitis, and another study found that it reduced intestinal motility, which can help to relieve symptoms of IBS.

2. Can CBD help with weight loss?

CBD may have the ability to help with weight loss. One study found that CBD was able to reduce food intake and body weight in rats, while another study observed that it increased energy expenditure through mitochondrial production.

3. Are there any side effects of taking CBD?

The most common side effect of taking CBD is drowsiness. Other potential side effects include dry mouth, and changes in appetite and weight. However, these side effects are typically mild and resolve on their own. If you experience any severe side effects, stop taking CBD and consult a doctor. CBD can interact with some medications including those that interact with grapefruit.

Conclusion: CBD has emerged as a star player in the world of gut health and weight loss. Its ability to work with the gut microbiome to improve overall health makes it ideal for anyone looking to slim down or just boost their general wellness. If you’re curious about giving CBD a try, we’ve got all the information you need on how to take it, what products are best, and the FAQs answered. Keep an eye out for more posts on CBD and its many benefits; there’s still so much to learn!

Disclaimer: The Blackhouse Botanicals Blog is for informational purposes only and does not replace professional medical advice. While we strive to provide quality links and studies, the use of information in this blog or materials linked from this blog is at the user’s own risk. Users should seek professional medical advice for any medical condition they may have and should seek the assistance of a healthcare professional for the treatment of any medical condition they may have. By using the user agrees that this website does not constitute a replacement for health and fitness advice from a professional provider.


Gorelick J, Assa-Glazer T, Zandani G, Altberg A, Sela N, Nyska A, Madar Z. THC, and CBD affect metabolic syndrome parameters including microbiome in mice fed high fat-cholesterol diet. J Cannabis Res. 2022 May 30;4(1):27. doi: 10.1186/s42238-022-00137-w. PMID: 35644678; PMCID: PMC9150295.

Abbotts KSS, Ewell TR, Butterklee HM, Bomar MC, Akagi N, Dooley GP, Bell C. Cannabidiol and Cannabidiol Metabolites: Pharmacokinetics, Interaction with Food, and Influence on Liver Function. Nutrients. 2022 May 21;14(10):2152. doi: 10.3390/nu14102152. PMID: 35631293; PMCID: PMC9144241.

Horn H, Böhme B, Dietrich L, Koch M. Endocannabinoids in Body Weight Control. Pharmaceuticals. 2018; 11(2):55.

Ramlugon S, Levendal RA, Frost CL. Time-dependent effect of phytocannabinoid treatments in fat cells. Phytother Res. 2018 Jun;32(6):1080-1089. doi: 10.1002/ptr.6047. Epub 2018 Feb 21. PMID: 29464872.

Parray, H.A., Yun, J.W. Cannabidiol promotes browning in 3T3-L1 adipocytes. Mol Cell Biochem 416, 131–139 (2016).

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